Nadifloxacin Gel

3.00 - 4.00 USD ($)/Unit

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Product Details:

Application Skin Care
Purity 99.89%
Molecular Formula Nadifloxacin Gel 0.1%
Formulations Type External Use Drugs
Formulations Form Cream
Treatments & Functions Skin Care
Gender/Age Group Suitable For All Ages
Supply Ability : 10000 Unit Per Day
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Price And Quantity

Minimum Order Quantity 100 Unit
Price Range 3.00 - 4.00 USD ($)/Unit

Product Specifications

Gender/Age Group Suitable For All Ages
Formulations Type External Use Drugs
Molecular Formula Nadifloxacin Gel 0.1%
Treatments & Functions Skin Care
Purity 99.89%
Formulations Form Cream
Application Skin Care
Dosage Guidelines As per doctor prescribe.
Storage Instructions Store in Cool

Trade Information

FOB Port Nhavasheva Port, Mundra Port, Hajira Port.
Payment Terms Cash Advance (CA), Cash in Advance (CID), Letter of Credit (L/C), Telegraphic Transfer (T/T), Western Union
Supply Ability 10000 Unit Per Day
Delivery Time 5-7 Days
Sample Available Yes
Sample Policy If order is confirmed we will reimburse the sample cost
Packaging Details lamitube packing
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Middle East, Africa
Main Domestic Market All India
Certifications EUGMP/WHOGMP/GMP.

Product Description

Nadifloxacin (INN, brand names Acuatim, Nadiflox, Nadoxin, Nadixa, activon) is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris. It is also used to treat bacterial skin infections.In vitro studies of nadifloxacin showed potent and broad-spectrum antibacterial activity against aerobic Gram-positive, Gram-negative and anaerobic bacteria, including. Propionibacterium acnes and Staphylococcus epidermidis.

Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication. Nadifloxacin in addition to determine a therapeutic antibacterial action, can have a sebostatic and anti-inflammatory action, thus contributing to the improvement of the clinical condition of the patient.

Following a single topical application of 10 g nadifloxacin 1% cream to normal human back skin, the highest plasma concentration was determined to be 107 ng/mL with an elimination half-life of 19.4 hours. Approximately 0.09% of the administered dose was excreted in the urine over 48 hours post- dosing.

The plasma concentration reached a steady state on Day 5 of repeated administration study when nadifloxacin 1% cream was applied at 5 g twice daily to normal healthy individuals for a period of 7 days. The plasma concentration reached a peak of 4.1 ng/ml at 8 hours post-final dosing with an elimination half-life of 23.2 hours. The urinary excretion rate reached 0.16% on Day 7.

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Nadifloxacin Gel

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