Product Description

Indications for Drugs ::

Pediatric eye examinations, Mydriasis,Cycloplegia, Uveitis, Iritis

Drug Dose ::

The normal adult dose is 1 or 2 drops of solution in each eye, as required. The administration of the drops can be repeated every 6-8 hours, depending on the treatment. The normal child dose (over 3 months old) is 1 drop of Cyclopentolate Hydrochloride 0.5% w/v in each eye. Children should be observed for 45 minutes after the administration of the drops.

Contraindication ::

Children under 3 months of age, Glaucoma, or people with a tendency to glaucoma because of a shallow anterior chamber, Conditions where the gut is not functioning properly, resulting in an obstruction in the bowel (paralytic ileus), Children with organic brain syndromes, including congenital or neuro-developmental abnormalities such as epilepsy. This medicine should not be used if history of allergies to one or any of its ingredients.

Drug Precautions ::

This medicine is for use in the eyes only and must not be taken by mouth. These eye drops can cause blurred vision, difficulty focusing and sensitivity to light. The effects can last for up to 24 hours. You must not drive or take part in hazardous activities unless you can see clearly. You should not wear soft contact lenses during treatment with these eye drops. This is because they contain a preservative called benzalkonium chloride, which can be absorbed by soft contact lenses and cause eye irritation.

Drug Side Effects ::

Eye irritation such as mild stinging, and sensitivity to light, Blurred vision. Other less common effects: dry mouth, flushing, dry skin, constipation, difficulties passing urine, a fast heartbeat, feeling sick, skin rash, giddiness and other changes in behaviou

Drug Mode of Action ::  

Cyclopentolate is an anticholinergic. It produces dilatation of the pupil and paralysis of accommodation. Has a shorter duration of action than atropine.

Drug Interactions ::

Plasma concentration may be increased with the use of cimetidine, diltiazem, disulfiram, methylphenidate, ritonavir, and verapamil. Side-effects are increased by adrenaline, amiodarone, general anesthetics, SSRIs, antihistamines, antimuscarinics, antipsychotics, anxiolytics and hypnotics, clozapine, disopyramide, diuretics, flecainide, MAOIs, moclobemide, moxifloxacin, nefopam, nicorandil, noradrenaline, phenothiazine, pimozide, procainamide, propafenone, quinidine, selegiline, sibutramine, sotalol, terfenadine, thioridazine, and tramadol. Effects of adrenergic neurone blockers, clonidine, barbiturates, nitrates, and primidone are reduced while effects of baclofen, opioid analgesics, and thyroid hormones are enhanced with concomitant use of cyclobenzaprine. Carbamazepine and rifampicin may increase metabolism of cyclobenzaprine. Effects may be antagonized by oestrogens. Avoid use with brimonidine, entacapone, artemether with lumefantrine, or sibutramine. CNS effects may be enhanced by other CNS depressants.